Neurosyphilis after treatment of latent syphilis with benzathine penicillin.
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منابع مشابه
Neurosyphilis after treatment of latent syphilis with benzathine penicillin.
Two patients developed neurosyphilis after treatment of latent syphilis with intramuscular benzathine penicillin. The cases confirm recent investigations that show that neither benzathine penicillin nor procaine penicillin in the standard doses results in treponemicidal concentrations of penicillin in cerebrospinal fluid. Neurosyphilis can be treated effectively by intravenous benzylpenicillin ...
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Arlene C. Seña, Mark Wolff, Frieda Behets, Kathleen Van Damme, David H. Martin, Peter Leone, Linda McNeil, and Edward W. Hook Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill; EMMES Corporation, Rockville, Maryland; Department of Epidemiology, University of North Carolina at Madagascar, Antananarivo; Department of Medicine, Louisiana State Uni...
متن کاملNicolau Syndrome after Intramuscular Benzathine Penicillin Injection
A 3-year-old boy was admitted to the emergency department with right lower limb pain, edema, and livedoid discoloration that occurred immediately after intramuscular injection of benzathine penicillin. The patient was diagnosed with Nicolau syndrome, a rare complication of intramuscular injection presumed to be related to the inadvertent intravascular injection. It was first reported following ...
متن کاملThe treatment of neurosyphilis with penicillin.
Penicillin has excited the whole world. It has done for the common bacterial infections what the sulphonamides had done for meningococcal meningitis and quinine for malaria. But penicillin was an antibacterial remedy: it was not to be expected that it would be potent against the protozoal infection of syphilis. Moreover it was soon discovered that penicillin given intramuscularly did not find i...
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BACKGROUND Treatment guidelines recommend the use of a single dose of benzathine penicillin G (BPG) for treating early syphilis in human immunodeficiency virus (HIV)-infected persons. However, data supporting this recommendation are limited. We examined the efficacy of single-dose BPG in the US Military HIV Natural History Study. METHODS Subjects were included if they met serologic criteria f...
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ژورنال
عنوان ژورنال: Sexually Transmitted Infections
سال: 1986
ISSN: 1368-4973
DOI: 10.1136/sti.62.2.129